A Clinical Evaluation of the Metabolic Response to an Organic Dietary Supplement

"A Clinical Evaluation of the Metabolic Response to an Organic Dietary Supplement"

James A. McHale, D.C. Director, Research and Development Atlantic Regional Osteoporosis Specialists, P.C.

Chief, Medical Advisory Board The Institute of Weight Management and Health

Peer Reviewed by:

Andrew Collins, D.P.M. Board Certified American Board of Medical Specialties (Podiatry)

Specialist, Podiatric Medicine and Surgery

"A Clinical Evaluation of the Metabolic Response to an Organic Dietary Supplement"

The purpose of this study was to evaluate the changes and differences among test subjects consuming an organic nutritional supplement and a control group. Muscle mass and basal metabolic rate were compared after thirty days.

Test subjects consisted of eighty men and women. Ages ranged between 19 to 51. Baseline data were obtained using a whole body bioimpedance unit.

"What is Whole Body Bioimpedance?"

By measuring the flow (or resistance to flow) of a weak electric current (800 uA)through various body components (especially the fluid found in lean muscle and fat tissue), the following data are obtained:

A. Body Fat (percent)

B. Metabolic Rate (calories per day expended, at rest) *By increasing metabolic rate, more calories (energy) is burned for fuel. Some examples of fuel that the body uses for energy include:

1. Sugar (carbohydrates)
2. Fats
3. Proteins

C. Body Fat (pounds) An effective weight loss program should target fat loss. Monitoring overall pounds of body fat lost is a safe, accurate way to trend healthy versus dangerous weight loss.

D. Lean Muscle Mass (pounds) As lean muscle mass increases, metabolic rate increases.

E. Hydration (total body water, liters)

F. Hydration (percent) Normal is around 66%-71%.

G. Target Weight (pounds) Ideal body weight includes adequate body fat plus water and lean muscle mass/lean weight. In addition to muscle mass, lean weight also includes tendon, ligament, and bone structures.

Lean tissue (muscle) offers very little resistance to this weak flow of electrons. Muscles have electrolytes and water- very good conductors. Body water volume is a very big factor in determining impedance. Fat tissue offers a lot of resistance to this weak flow of electrons due to its low water content.

Four leads (two on the hand/wrist and two on the ankle/foot) are placed to compare the voltage drop between electrodes to obtain the impedance result. The impedance result is compared to total body water. Computer generated lean body mass s then calculated. By subtracting lean body mass (pounds) from the total body weight, we are left with the amount of fat in pounds.

Testing via whole body bioimpedance is extremely accurate. Body fat is within 1.5 percent, compared to hydrostatic testing. This technology is utilized in leading medical centers, medical colleges and universities, as well as in the US Army, Navy, Air Force, and Marine Corps.

Data Parameters:

All participants were engaged in regular exercise regimens at a fitness facility that included cardiovascular training, weight resistance, and stretching. Frequency was a minimum of three times per week. They were instructed not to alter their training during the thirty day test period.

Control Group Participants (Group A) consisted of 21 men and 19 women. Fourteen men (66%) consumed various brands and forms of daily multiple vitamins (tablets, powders, softgels, and liquids). 15 women (79%) also consumed various types of daily multiple vitamins.

Group B Participants (23 men, 17 women) consumed one ounce per day of an organic dietary supplement (Panacea ™) for thirty days.

Each one ounce serving of the peach/mango flavored liquid supplement contained the following:

Carbohydrates: 5g (natural sugars 4g)
Sodium: 4mg
Dietary Fiber: 1g
Protein: 1g
Vitamin A (beta carotene) 10,000 IU
Vitamin B-1 (thiamin) 15mg
Vitamin B-2 (riboflavin) 20mg
Vitamin B-3 (niacinamide) 20mg
Vitamin B-5 (Pantothenic acid) 10mg
Vitamin B-6 (pyrodoxine -5-phosphate) 20mg
Vitamin B-12 (Cyanocobalamine) 60mcg
Vitamin C (buffered complex) 600mg
Vitamin D (cholecalciferol) 400iu
Vitamin E (d-alpha-tocopherol) 33iu
Vitamin K 40mcg
Biotin 300mcg
Choline 140mg
Folic Acid 800mcg
Alpha-lipoic Acid 75mg
Bioflavonoid citrus complex (quercetin and OPC) 75mg
Inositol 25mg
PABA (para-aminobenzoic acid) 25mg
Grapeseed Extract (92% proanthocyanidins) 25mg
Co-enzyme Q-10 3mg
Gamma oryzanol (cycloartenol ferulic acid) 50mg
Omega 3-6-9 Essential Fatty Acids (ALA/DHA/EPA/GLA) 150mg
L-Glutathione 50mg
Dimethylglycine (DMG) 50mg
Oxygen (dissolved and stabilized) 427mg/liter
Carbon (organic, essential living elements and nutrients) 144,500mg/liter
Fulvic Acid (organic, systemic nutritional carrier and detoxifier) 9.2%
Calcium 1,000mg
Chromium 200mcg
Copper 2mg
Iodine (sea kelp) 177mcg
Iron 5mg
Magnesium 420mg
Manganese 3mg
Phosphorus 700mg
Potasssium 2,000mg
Selenium 70mcg
Zinc 15mg

Other ingredients include: Rapid Immune Defense Blend™, Yeast and Parasite Eliminator Matrix™, Blood, Cellular and Intestinal Cleanser Matrix ™. Immune Boosting and Anti-inflammatory Matrix™, Amino Acid Matrix™ (all essential and non-essential amino acids), Digestive Enzyme and Probiotic Matrix™ (non-dairy 5.0 billion cultures total count), Herbal Memory, Mental Clarity, Energy & Vitality Matrix™, Antioxidant Rich Vegetable Garden Matrix™, Antioxidant Rich Fruit Orchard Matrix™, Full Spectrum Organic Trace Mineral Matrix™, proprietary ultra purified and reverse osmosis filtered water, 100% organically bound microcystalized fructose, 100% organically bound natural peach and mango flavors, 100% organic homeostatic AquaComplexes™ in a base of 100% organically bound Bach flowers.

The results of this study demonstrate a clear difference in muscle mass, body fat, and metabolism results between the two groups:

The control group follow-up data consisted of 28 individuals (70%) (17 men, 11 women). Twelve people (30%) failed to return for follow up testing at the end of the thirty day program.

A. Body Fat Percent decreased 1.3%

B. Metabolic Rate increased 42 calories

C. Body Fat decreased 1.7 pounds

D. Lean Muscle Mass increased an average of 1.15 pounds

E. Hydration percent/total body water was essentially unchanged

F. 9 participants were at or near (within three pounds) of their ideal body weight


The Group B follow-up data consisted of 31 individuals (78%) (16 men, 15 women) Nine people (22%) failed to return for follow-up testing at the end of the thirty day program.

A. Body Fat Percent decreased 2.2%

B. Metabolic Rate increased 56 calories

C. Body Fat decreased 2.6 pounds

D. Lean Muscle Mass increased an average of 1.9 pounds

E. Hydration percent/total body water was essentially unchanged

F. 7 participants were at or near (within three pounds) of their ideal body weight


Data Evaluation:

The group that consumed the liquid organic nutritional supplement fared better than the control group in several areas: Their body fat decreased to a greater extent (41%), metabolic rate increased (25%), fat loss in pounds at the end of the study was almost one pound more compared to the control group. Lean muscle mass was increased in both groups, but this group gained about three quarters of a pound more than the control group. This is supported by the fact that their metabolic rate increased to a greater extent as well; increasing lean muscle mass increases the metabolic rate.

Both groups were extremely well hydrated during both phases of testing.

Discussion:

More women returned for follow-up evaluation in Group B (15) versus Group A (11). Women generally maintain higher body fat content than men. That may account for Group B to be more likely to lose more body fat. However, when we look at the follow-up data for muscle mass development we find that Group A had one more man evaluated compared to Group B. Men tend to increase muscle mass more dramatically than women. Interestingly, Group B gained about three quarters of a pound more muscle than Group A.

Both groups reported the following on survey:

A. Being included in the study encouraged them to focus more on their exercise technique, schedule, and overall health during the 30 day period.

B. 87% of Group B reported more energy

C. 22% of Group A reported more energy

D. 80% of Group B (32 of 40) liked the taste of the supplement

E. 26 of 31 (84%) of Group B would use it again

F. 24 of 28 (86%) of the Control Group (A) reported that they would try the supplement based on the study results.

Conclusion:

Panacea™ organic dietary supplement performed well in this study. There is no way to know for sure exactly why Group B did so well. Since Panacea™ has high doses of the B Vitamins, this may account for the increased energy reported. Subjects are instructed to hold the supplement in the mouth undiluted---for thirty seconds. This may allow for sublingual absorption of the B vitamins-rapidly absorbed into the bloodstream for quick use in physiologic functions. Increased energy may provide an environment conducive to high intensity training. One other idea to be proposed involves the Amino Acid Matrix™. Amino acids are building blocks of protein---muscle is composed primarily of protein. By providing adequate amino acid levels, muscle production may have been improved.

Clearly, a larger population needs to be studied, over a longer period of time. It is this authors contention that the Panacea™ organic dietary supplement was an integral part of the improvement in metabolism and lean muscle mass production in humans during the thirty day trial.

Questions or Comments? mrmack2@yahoo.com